HPRT Testi OECD 476 İn Vitro Memeli Hücresi Gen Mutasyon Testi:

It is used to detect gene mutations induced by chemicals The genetic endpoints used in this test measure mutations in the hypoxanthine guanine phosphoribosyl transferase (HPRT) transgene.

Other Tests

Test for Mammalian Chromosome Abnormalities

Chromosomal abnormalities (CA) refer to a numerical or structural change in the chromosome. CA test is used to detect various structural and numerical abnormalities by mutagens

Hemolysis Test

Blood interaction tests are performed to determine the possible effects of medical devices that interact directly or indirectly with blood.

Cytotoxicity Test

Cytotoxicity is carried out with the aim of determining the toxic effects that can be caused by the contact of medical devices interacting with the body.

Stability Test

It is carried out to determine the time effects on the physical properties of medicinal products and their packages.

Bioburden Test

Bioburden is defined as the number of living microorganisms present in a given amount of material before medical equipment or devices are subjected to the sterilization procedure.